Mortality in acromegaly diagnosed in the elderly in Spain is higher in women compared to the general Spanish population.
Betina BiagettiPedro IglesiasRocío Villar-TaiboMaría-Dolores MoureMiguel PajaMarta Araujo-CastroJessica AresCristina Álvarez-EscolaAlmudena VicenteÈlia Álvarez GuivernauIria Novoa-TestaFernando Guerrero PerezRosa CámaraBeatriz LecumberriCarlos García GómezIgnacio BernabéuLaura ManjónSonia GaztambideFernando CordidoSusan M WebbEdelmiro Luis Menéndez-TorreJuan J DíezRafael SimóManel Puig-DomingoPublished in: The Journal of clinical endocrinology and metabolism (2023)
The mortality in patients with acromegaly diagnosed in the elderly was no different between both periods and there was no overall SMR difference from the general Spanish population. However, the SMR was higher in women. As CVD is the leading cause of mortality, it seems advisable to initiate an intense CVD protective treatment as soon as acromegaly is diagnosed, particularly in women, in addition to tight acromegaly control in order to prevent excess mortality.