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High-throughput screen identifies 5-HT receptor as a modulator of AR and a therapeutic target for prostate cancer.

Momoe ItsumiMasaki ShiotaYohei SekinoMiho UshijimaEiji KashiwagiArio TakeuchiJunichi InokuchiShunichi KajiokaTakeshi UchiumiMasatoshi Eto
Published in: The Prostate (2020)
Taken together, this study identifies 5-HT5A receptor as a promising therapeutic target for prostate cancer via its interaction with AR signaling.
Keyphrases
  • prostate cancer
  • high throughput
  • radical prostatectomy
  • genome wide
  • single cell
  • gene expression
  • binding protein
  • dna methylation