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MNX1-AS1 Promotes Phase Separation of IGF2BP1 to Drive c-Myc-Mediated Cell-Cycle Progression and Proliferation in Lung Cancer.

Qingqing ZhuChongguo ZhangTianyu QuXiyi LuXuezhi HeWei LiDandan YinLiang HanRen-Hua GuoErbao Zhang
Published in: Cancer research (2022)
MNX1-AS1 drives phase separation of IGF2BP1 to increase c-Myc and E2F1 signaling and to activate cell-cycle progression to promote proliferation in NSCLC.
Keyphrases
  • cell cycle
  • cell proliferation
  • signaling pathway
  • pi k akt
  • small cell lung cancer
  • growth hormone
  • advanced non small cell lung cancer
  • epidermal growth factor receptor