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[Histological changes in intraperitoneal onlay mesh (IPOM) with synthetic and biological meshes. Results of the chronic experiment].

A M BelousovV P ArmashovDmitry ShkarupaT Yu AnushchenkoT S FilipenkoN M BlumP A PotapovK O TimofeevaA A PutulyanN L Matveev
Published in: Khirurgiia (2023)
The conducted morphological and morphometric study showed that the most balanced ratio of the components of the newly formed fibrous tissue and blood vessels is observed when using implants with a fluoropolymer coating FTOREX. At the same time, the remaining basic peritoneum actively participated in the formation of the neoperitoneum. The Ventralight ST and Symbotex meshes also contributed to the formation of a full-fledged fibrous tissue and adequate vascular proliferation, however, they prevented the preservation of the underlying peritoneum, which practically excluded its participation in the formation of the neoperitoneum. The REPEREN mesh and decellularized porcine peritoneum led to the least balanced cell and vascular proliferation and the greatest fibroplastic reaction, which could further negatively affect the state of the formed scar.
Keyphrases
  • signaling pathway
  • single cell
  • stem cells
  • mesenchymal stem cells
  • soft tissue
  • bone marrow