Peripheral blood mononuclear cell gene expression and cytokine profiling in patients with intermittent claudication who exhibit exercise induced acute renal injury.

Pasha Normahani Joseph J BoyleLuke CavePaul BrookesKevin J WoollardUsman Jaffer

Published in: PloS one (2022)

Our results suggest that some patients with IC have an altered immune status making them 'vulnerable' to systemic inflammation and renal injury following exercise. We have identified a panel of genes which are differentially expressed in this group of patients.

Keyphrases

peripheral blood
gene expression
high intensity
end stage renal disease
single cell
ejection fraction
newly diagnosed
dna methylation
resistance training
genome wide
cell therapy
stem cells
peritoneal dialysis