Assessing cardiac mechanics through left ventricular haemodynamic forces.
Alberto AimoGiorgia PanichellaIacopo FabianiManuel GarofaloAngela Ilaria FanizziMaddalena RagagninAlessandra MilazzoChiara ZocchiAnnamaria Del FrancoGianni PedrizzettiIacopo OlivottoMichele EmdinPublished in: European heart journal. Imaging methods and practice (2024)
Haemodynamic forces (HDFs), which represent the forces exchanged between blood and surrounding tissues, are critical in regulating the structure and function of the left ventricle (LV). These forces can be assessed on cardiac magnetic resonance or transthoracic echocardiography exams using specialized software, offering a non-invasive alternative for measuring intraventricular pressure gradients. The analysis of HDFs can be a valuable tool in improving our understanding of cardiovascular disease and providing insights beyond traditional diagnostic and therapeutic approaches. For instance, HDF analysis has the potential to identify early signs of adverse remodelling and cardiac dysfunction, which may not be detected by standard imaging methods such as bidimensional or speckle-tracking echocardiography. This review aims to summarize the principles of HDF analysis and to reappraise its possible applications to cardiac disorders.
Keyphrases
- left ventricular
- magnetic resonance
- cardiovascular disease
- hypertrophic cardiomyopathy
- mitral valve
- cardiac resynchronization therapy
- acute myocardial infarction
- heart failure
- left atrial
- pulmonary hypertension
- aortic stenosis
- gene expression
- computed tomography
- high resolution
- type diabetes
- magnetic resonance imaging
- emergency department
- risk assessment
- acute coronary syndrome
- climate change
- photodynamic therapy
- coronary artery
- transcatheter aortic valve replacement
- cardiovascular risk factors
- ejection fraction