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Data Archive for the BRAIN Initiative (DABI).

Dominique DuncanRachael GarnerSarah BrinkerhoffHarrison C WalkerNader PouratianArthur W Toga
Published in: Scientific data (2023)
Data sharing is becoming ubiquitous and can be advantageous for most biomedical research. However, some data are inherently more amenable to sharing than others. For example, human intracranial neurophysiology recordings and associated multimodal data have unique features that warrant special considerations. The associated data are heterogeneous, difficult to compare, highly specific, and collected from small cohorts with treatment resistant conditions, posing additional complications when attempting to perform generalizable analyses across projects. We present the Data Archive for the BRAIN Initiative (DABI) and describe features of the platform that are designed to overcome these and other challenges. DABI is a data repository and portal for BRAIN Initiative projects that collect human and animal intracranial recordings, and it allows users to search, visualize, and analyze multimodal data from these projects. The data providers maintain full control of data sharing privileges and can organize and manage their data with a user-friendly and intuitive interface. We discuss data privacy and security concerns, example analyses from two DABI datasets, and future goals for DABI.
Keyphrases
  • electronic health record
  • big data
  • quality improvement
  • endothelial cells
  • data analysis
  • multiple sclerosis
  • white matter
  • brain injury
  • artificial intelligence
  • blood brain barrier
  • pain management
  • cerebral ischemia