Gene mutation spectrum of patients with myelodysplastic syndrome and progression to acute myeloid leukemia.

Ming LiuFang WangYang ZhangXue ChenPanxiang CaoDaijing NieJiancheng FangMingyu WangMingyue LiuHongxing Liu

Published in: International journal of hematologic oncology (2021)

Our data demonstrate that there is a cumulative accumulation of gene mutations, especially in transcription factor genes, during disease progression in MDS and MDS/AML.

Keyphrases

acute myeloid leukemia
transcription factor
genome wide identification
allogeneic hematopoietic stem cell transplantation
electronic health record
genome wide
big data
dna binding
bioinformatics analysis
dna methylation
machine learning
artificial intelligence
data analysis
acute lymphoblastic leukemia