Obesity is linked to disease severity in moderate to severe atopic dermatitis-Data from the prospective observational TREATgermany registry.
Stephan TraidlMoritz M HollsteinNadine KroegerSascha FischerAnnice HeratizadehLuise HeinrichBarbara KindDoreen SiegelsSusanne AbrahamThomas SchäferMatthias AugustinInken HarderAndreas PinterKnut SchäkelAndreas WollenbergKonstantin ErtnerJutta Ramaker-BrunkeAnne BongSven QuistHannah Gorriahn-MaiterthFlorian SchenckMichael SticherlingIsaak EffendyBeate SchwarzChristiane HandrickAndrea AsmussenStephan WeidingerJochen SchmittThomas Werfelnull nullPublished in: Journal of the European Academy of Dermatology and Venereology : JEADV (2024)
In this large and well-characterized AD patient cohort, obesity is significantly associated with physician- and patient-assessed measures of AD disease severity. However, the corresponding effect sizes were low and of questionable clinical relevance. The overall prevalence of obesity among the German AD patients was lower than in studies on other AD cohorts from different countries, which confirms previous research on the German population and suggests regional differences in the interdependence of AD and obesity prevalence.
Keyphrases
- insulin resistance
- metabolic syndrome
- weight loss
- high fat diet induced
- type diabetes
- weight gain
- end stage renal disease
- risk factors
- atopic dermatitis
- case report
- primary care
- newly diagnosed
- chronic kidney disease
- skeletal muscle
- adipose tissue
- machine learning
- early onset
- peritoneal dialysis
- high intensity
- artificial intelligence
- patient reported outcomes
- case control