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Influence of puberty timing on adiposity and cardiometabolic traits: A Mendelian randomisation study.

Joshua A BellDavid CarslakeKaitlin H WadeRebecca C RichmondRyan J LangdonEmma E VincentMichael V HolmesNicholas John TimpsonGeorge Davey Smith
Published in: PLoS medicine (2018)
Our results suggest that puberty timing has a small influence on adiposity and cardiometabolic traits and that preventive interventions should instead focus on reducing childhood adiposity.
Keyphrases
  • insulin resistance
  • weight gain
  • genome wide
  • physical activity
  • metabolic syndrome
  • adipose tissue
  • type diabetes
  • dna methylation
  • gene expression