Prospective Association Between Inflammatory Markers and Knee Cartilage Volume Loss and Pain Trajectory.

Feng PanJing TianFlavia CicuttiniGraeme Jones

Published in: Pain and therapy (2021)

IL-6 was independently associated with compartment-specific CV loss and worse pain trajectory, but the other markers studied were not, suggesting that components of inflammation are implicated in the pathogenesis of cartilage loss and developing a worse pain course.

Keyphrases

chronic pain
pain management
neuropathic pain
oxidative stress
total knee arthroplasty
extracellular matrix
knee osteoarthritis
solid state