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Effects of remifentanil on esophageal and esophagogastric junction (EGJ) bolus transit in healthy volunteers using novel pressure-flow analysis.

Charles CockS H DoeltgenT OmariJ Savilampi
Published in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2017)
Remifentanil-induced effects were different for proximal and distal esophagus, with a reduced time for trans-sphincteric bolus flow at the EGJ, suggestive of central and peripheral μ-opioid agonism. There were no functional consequences in healthy subjects.
Keyphrases
  • chronic pain
  • high glucose
  • pain management
  • diabetic rats
  • minimally invasive