Outcomes of SDHB Pathogenic Variant Carriers.
Dahlia F DavidoffRichard De Abreu LourencoVenessa H M TsangDiana E BennRoderick John Clifton-BlighPublished in: The Journal of clinical endocrinology and metabolism (2024)
Penetrance for PPGLs in SDHB PV carriers increases linearly with age. Affected carriers are at risk of developing and dying of metastatic disease, or of developing second tumors. Lifelong surveillance is appropriate.