In Silico TRials guide optimal stratification of ATrIal FIbrillation patients to Catheter Ablation and pharmacological medicaTION: the i-STRATIFICATION study.
Albert DasíClaudia NagelMichael T B PopeRohan S WijesurendraTimothy R BettsRafael Sachetto OliveiraAxel LoeweAlfonso Bueno-OrovioBlanca RodriguezPublished in: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology (2024)
In silico trials identify optimal strategies for AF treatment based on virtual patient characteristics, evidencing the power of human modelling and simulation as a clinical assisting tool.
Keyphrases
- atrial fibrillation
- catheter ablation
- left atrial
- left atrial appendage
- end stage renal disease
- oral anticoagulants
- ejection fraction
- molecular docking
- endothelial cells
- newly diagnosed
- heart failure
- direct oral anticoagulants
- prognostic factors
- healthcare
- percutaneous coronary intervention
- left ventricular
- induced pluripotent stem cells
- combination therapy
- acute coronary syndrome
- adverse drug
- replacement therapy