The use of non-invasive stool tests for verification of Helicobacter pylori eradication and clarithromycin resistance.
Michiel C MommersteegStella A V NieuwenburgLeonieke M M WoltersBuddy H C M RooversHanneke A J van VuurenAuke P VerhaarMarco J BrunoErnst J KuipersMaikel P PeppelenboschManon C W SpaanderGwenny Manel FuhlerPublished in: United European gastroenterology journal (2023)
H. pylori antigen testing on FIT stool samples to verify H. pylori eradication is feasible and has similar accuracy as H. pylori antigen testing on dry stool samples. Dry stool, but not FIT, was suitable for non-invasive identification of H. pylori clarithromycin resistance by rt-PCR personalizing antibiotic treatment strategies without the need for invasive diagnostics is desirable, as the cure rate of first-line empirical H. pylori treatment remains low.