What Is the Cause of Toxicity of Silicone Oil?
Ying ChenYan Lam IpLiangyu ZhouPik Yi LiYee Mei ChanWai Ching LamKenneth Kai Wang LiDavid H SteelYau Kei ChanPublished in: Materials (Basel, Switzerland) (2021)
Most LMWCs, in both liquid and emulsified forms, can induce acute cytotoxicity. In addition, cyclic LMWCs are suspected to have higher cytotoxicity than their linear counterparts. Therefore, LMWCs are suspected to be the main cause of the long-term toxicity of ophthalmic SilOil, due to their toxicity and propensity to cause ophthalmic SilOil to emulsify. The amount of LMWCs should be considered as the paramount parameter when referring to the quality of SilOil.