The endo-lysosomal system of bEnd.3 and hCMEC/D3 brain endothelial cells.

Andrea Erzsebet TóthSimone S E NielsenWeronika TomakaN Joan AbbottMorten S Nielsen

Published in: Fluids and barriers of the CNS (2019)

Taken together our data identify differences in the trafficking network of brain endothelial cells, essentially mapping the endo-lysosomal system of in vitro blood-brain barrier models. This knowledge is valuable for planning the optimal route across the blood-brain barrier and advancing drug delivery to the brain.

Keyphrases

blood brain barrier
endothelial cells
cerebral ischemia
resting state
white matter
drug delivery
healthcare
high resolution
multiple sclerosis
subarachnoid hemorrhage
big data
mass spectrometry
high density
artificial intelligence
network analysis