Features of T1 pancreatic cancer and validation of the eighth edition AJCC staging system definition using a Korean-Japanese joint cohort and the SEER database.
Wooil KwonJin Seok HeoIn-Woong HanChang Moo KangHo Kyoung HwangSong Cheol KimSang-Jae ParkYoo-Seok YoonYong Hoon KimChang-Sup LimSeung Yeoun LeeTaesung ParkHideki TakamiNobuyuki WatanabeYasuhiro ShimizuMasataka OkunoHiroki YamaueManabu KawaiHirono SeikoYuichi NagakawaHiroaki OsakabeTeiichi SugiuraHirochika ToyamaMasayuki OhtsukaMichiaki UnnoItraru EndoMinoru KitagoJin-Young JangPublished in: Journal of hepato-biliary-pancreatic sciences (2023)
Despite its small size, T1 PDAC displayed aggressive behavior warranting active local and systemic treatment. The subcategorization by the eighth edition of the AJCC staging system was not adequate for PDAC, and better subcategorization methods need to be explored. In addition, the role of extrapancreatic extension in the staging system should be reconsidered.
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