In summary, the present study suggests that M. vaccae may contribute to alleviating airway inflammation and remodeling in allergic asthma by potentially modulating autophagy and the PI3K/Akt signaling pathway. These discoveries offer a promising avenue for the development of therapeutic interventions targeting allergic airway inflammation.
Keyphrases
- signaling pathway
- pi k akt
- allergic rhinitis
- mouse model
- epithelial mesenchymal transition
- induced apoptosis
- cell cycle arrest
- chronic obstructive pulmonary disease
- mycobacterium tuberculosis
- high glucose
- physical activity
- atopic dermatitis
- diabetic rats
- cell death
- lung function
- endoplasmic reticulum stress
- endothelial cells
- drug induced
- drug delivery
- air pollution