Review on ultrasound-guided photoacoustic imaging for complementary analyses of biological systems in vivo .
Haeni LeeWonseok ChoiChulhong KimByullee ParkJeesu KimPublished in: Experimental biology and medicine (Maywood, N.J.) (2023)
Photoacoustic imaging has been developed as a new biomedical molecular imaging modality. Due to its similarity to conventional ultrasound imaging in terms of signal detection and image generation, dual-modal photoacoustic and ultrasound imaging has been applied to visualize physiological and morphological information in biological systems in vivo . By complementing each other, dual-modal photoacoustic and ultrasound imaging showed synergistic advances in photoacoustic imaging with the guidance of ultrasound images. In this review, we introduce our recent progresses in dual-modal photoacoustic and ultrasound imaging systems at various scales of study, from preclinical small animals to clinical humans. A summary of the works reveals various strategies for combining the structural information of ultrasound images with the molecular information of photoacoustic images.
Keyphrases
- fluorescence imaging
- deep learning
- ultrasound guided
- high resolution
- magnetic resonance imaging
- convolutional neural network
- optical coherence tomography
- photodynamic therapy
- health information
- stem cells
- mesenchymal stem cells
- machine learning
- mass spectrometry
- computed tomography
- social media
- contrast enhanced ultrasound
- loop mediated isothermal amplification
- label free
- single molecule