To weight or not to weight? The effect of selection bias in 3 large electronic health record-linked biobanks and recommendations for practice.

Maxwell SalvatoreRitoban KunduXu ShiChristopher R FrieseSeunggeun LeeLars G FritscheAlison M MondulDavid HanauerCeleste Leigh PearceBhramar Mukherjee

Published in: Journal of the American Medical Informatics Association : JAMIA (2024)

EHR-linked biobanks should report recruitment and selection mechanisms and provide selection weights with defined target populations. Researchers should consider their intended estimands, specify source and target populations, and weight EHR-linked biobank analyses accordingly.

Keyphrases

electronic health record
weight loss
body mass index
physical activity
clinical decision support
weight gain
adverse drug
body weight
primary care
healthcare
genetic diversity
quality improvement