A low serum alkaline phosphatase may signal hypophosphatasia in osteoporosis clinic patients.

Elisabeth NgClaudia AshkarEgo SeemanHans G SchneiderHanh NguyenPeter R EbelingShoshana Sztal-Mazer

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2022)

Persistently low ALP in osteoporosis clinic attendees is easy to identify and signals the possibility of hypophosphatasia, a condition that may be mistaken for osteoporosis and incorrectly treated with antiresorptive therapy.

Keyphrases

postmenopausal women
bone mineral density
newly diagnosed
primary care
replacement therapy
ejection fraction
patient reported outcomes
body composition
mesenchymal stem cells
smoking cessation