Neurite orientation dispersion and density imaging quantifies microstructural impairment in the thalamus and its connectivity in amyotrophic lateral sclerosis.

Yun-Bin CaoYe WuQiu-Yi DongNao-Xin HuangZhang-Yu ZouHua-Jun Chen

Published in: CNS neuroscience & therapeutics (2024)

Microstructural impairment in the thalamus and thalamocortical connectivity is the hallmark of ALS. NODDI improved the detection of disrupted thalamo-cortical connectivity in ALS.

Keyphrases

white matter
resting state
functional connectivity
multiple sclerosis
deep brain stimulation
amyotrophic lateral sclerosis
high resolution
real time pcr
loop mediated isothermal amplification
photodynamic therapy