Off-tenofovir hepatitis flares in HBeAg-negative patients occur earlier, more frequent and severe than those off-entecavir therapies.

Yen-Chun LiuWen-Juei JengChien-Wei PengRong-Nan ChienYun-Fan Liaw

Published in: Liver international : official journal of the International Association for the Study of the Liver (2022)

Hepatitis flare occurred more frequently, earlier, and more severe in off-TDF than off-ETV patients. More stringent off-therapy monitoring within 6 months off-TDF is mandatory whereas more attention is needed after 6 months off-ETV.

Keyphrases

end stage renal disease
newly diagnosed

chronic kidney disease
peritoneal dialysis

early onset
working memory

smoking cessation
antiretroviral therapy