Long range PCR-based deep sequencing for haplotype determination in mixed HCMV infections.
Nadja BraitBüşra KülekçiIrene GoerzerPublished in: BMC genomics (2022)
Quantitative haplotype determination by long amplicon sequencing provides a novel approach for HCMV strain characterisation in mixed infected samples which can be scaled up to cover the majority of the genome by multi-amplicon panels. This will substantially improve our understanding of intra-host HCMV strain diversity and its dynamic behaviour.