Risk Factors for and Mechanisms of COlistin Resistance Among Enterobacterales: Getting at the CORE of the Issue.
John P MillsLaura J RojasSteve H MarshallSusan D RudinAndrea M HujerLuke NayakMichael A BachmanRobert A BonomoKeith S KayePublished in: Open forum infectious diseases (2021)
Increased age and prior antibiotic receipt were associated with increased risk for patients with CORE and for patients with COSE. Mcr-1, pmrA/B, and mgrB were the predominant colistin resistance-associated mutations identified among E. coli and K. pneumoniae, respectively. Mechanisms of colistin resistance among Enterobacter species could not be determined.