Natural history, risk factors and clinical features of primary hypogonadism in ageing men: Longitudinal Data from the European Male Ageing Study.
Tomás AhernAgnieszka SwiecickaRobert J A H EendebakEmma L CarterJoseph D FinnStephen R PyeTerence W O'NeillLeen AntonioBrian KeevilGyörgy BartfaiFelipe F CasanuevaGianni FortiAleksander GiwercmanThang S HanKrzysztof KulaMichael E J LeanNeil PendletonMargus PunabGiulia RastrelliMartin K RutterDirk VanderschuerenIlpo T HuhtaniemiFrederick C W Wunull nullPublished in: Clinical endocrinology (2016)
Primary testicular failure in men is uncommon and predicted by old age and chronic illness. Some clinical features attributable to androgen deficiency, but not others, accompanied the T decline in men who developed biochemical PHG. Whether androgen replacement can improve sexual and/or physical function in elderly men with PHG merits further study.