Increased prevalence of nodular thyroid disease in patients with Klinefelter syndrome.

Rosa di FraiaDaniela EspositoLucia Digitale SelvaggioFrancesca AllossoRoberto AlfanoMario RotondiGiancarlo BalerciaGiacomo AccardoDaniela Pasquali

Published in: Endocrine (2023)

We observed a significantly higher prevalence of nodular thyroid disease in KS compared to the control group. The increase in nodular thyroid disease is likely linked to low levels of FT4, inappropriate TSH secretion, and/or genetic instability.

Keyphrases

risk factors
genome wide
dna methylation