Differential regulation of Ca v 3.2 and Ca v 2.2 calcium channels by CB 1 receptors and cannabidiol.

Erika K HardingIvana A SouzaMaria A GandiniVinícius M GadottiMd Yousof AliSun HuangFlavia T T AntunesTuan TrangGerald W. Zamponi

Published in: British journal of pharmacology (2023)

receptors and CBD. This advances our understanding of how different cannabinoids produce analgesia through action at different voltage-gated calcium channels and could influence the development of novel cannabinoid-based therapeutics for treatment of chronic pain.

Keyphrases

chronic pain
pain management
small molecule
protein kinase
ultrasound guided
combination therapy