Evaluating the safety and efficacy of mesenchymal stem cell-derived exosomes for treatment of refractory perianal fistula in IBD patients: clinical trial phase I.
Hojjatollah NazariForoogh AlborziAsieh Heirani-TabasiAlireza HadizadehReza Akbari AsbaghBehnam BehboudiMohammad Sadegh FazeliMojgan RahimiMohammad Reza KeramatiAmir KeshvariAlireza KazemeiniMasoud SoleimaniSeyed Mohsen Ahmadi TaftiPublished in: Gastroenterology report (2022)
Injection of exosomes extracted from MSCs demonstrates safety and a satisfactory therapeutic effect, as evidenced in this and other studies, and may play a significant role in the future treatment of gastrointestinal fistulas.