Patient-derived lymphoma spheroids integrating immune tumor microenvironment as preclinical follicular lymphoma models for personalized medicine.

Carla Faria Fabien Gava Pauline Gravelle Juan Garcia Valero Cèlia Dobaño-López Nathalie Van Acker Cathy QuelenGael JalowickiRenaud Morin Cédric RossiJean-Michel LagardeJean-Jacques Fournié Loic Ysebaert Camille Laurent Patricia Pérez-Galán Christine Bezombes

Published in: Journal for immunotherapy of cancer (2023)

In summary, FL-PDLS is a robust patient-derived 3D system that can be used as a tool to mimic FL pathology and to test novel immunotherapeutic approaches in a context of personalized medicine.

Keyphrases

diffuse large b cell lymphoma
cell therapy
stem cells
bone marrow