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Insights on the performance of phenotypic tests versus genotypic tests for the detection of carbapenemase-producing Gram-negative bacilli in resource-limited settings.

Noha A KamelSally T TohamyIbrahim S YahiaKhaled M A Aboshanab
Published in: BMC microbiology (2022)
The current study provides an update on the performance of the phenotypic tests which are varied depending on the tested bacterial genera and the type of the carbapenemase. The overall sensitivity/specificity values for detection of CPO were 65.62%/100% for MHT, 68.65%/100% for mCIM, 55.22%/100% for CDT and 89.55%/75% for BCT. Based on its respective diagnostic efficiency and rapid turnaround time, BCT is more likely to be recommended in a resource-limited settings particularly, when molecular tests are not available.
Keyphrases
  • gram negative
  • multidrug resistant
  • loop mediated isothermal amplification
  • acinetobacter baumannii
  • klebsiella pneumoniae
  • drug resistant
  • label free
  • real time pcr
  • escherichia coli
  • cystic fibrosis