Kidney transplantation from an HIV-positive deceased donor to an HIV-positive recipient.
Christiane Lyngberg-LarsenAlex Lund LaursenLara Aygen ØzbayPublished in: BMJ case reports (2022)
Preliminary data on HIV-positive donor to HIV-positive recipient kidney transplantation suggest promising patient outcomes without adverse events. This is an important step in expanding the donor pool and opportunity for transplantation in HIV-positive patients.We herein report the first case of HIV-positive donor to HIV-positive recipient kidney transplantation in Denmark. Our patient has demonstrated a successful post-transplant course with excellent 1-year graft function, no rejection episodes, good virological control with undetectable HIV RNA, no signs of HIV-associated nephropathy, and no superinfections or opportunistic infections.This case corroborates findings from previous studies showing that kidney transplantation from carefully selected HIV-infected donors to carefully selected HIV-infected recipients seems to be a safe and effective treatment option, and supports the opportunity to expand the organ donor pool for this group of patients with end-stage renal disease.
Keyphrases
- hiv positive
- kidney transplantation
- antiretroviral therapy
- hiv infected
- end stage renal disease
- men who have sex with men
- human immunodeficiency virus
- hiv infected patients
- hiv aids
- chronic kidney disease
- south africa
- peritoneal dialysis
- hiv testing
- ejection fraction
- stem cells
- machine learning
- electronic health record
- hepatitis c virus
- newly diagnosed
- case report
- artificial intelligence
- bone marrow
- big data