Negative Regulation of Serine Threonine Kinase 11 (STK11) through miR-100 in Head and Neck Cancer.
Gabriela Figueroa-GonzálezJosé F Carrillo-HernándezItzel Perez-RodriguezDavid Cantú de LeónAlma D Campos-ParraAntonio Daniel Martinez-GutierrezJossimar Coronel-HernándezVerónica García-CastilloCesar López-CamarilloOscar Peralta-ZaragozaNadia J Jacobo-HerreraMariano Guardado-EstradaCarlos Perez-PlasenciaPublished in: Genes (2020)
This is, to our knowledge, the first report of miR-100-3p targeting STK11 in HNC. Together, these findings may support the importance of regulation of STK11 through post-transcriptional regulation in HNC and the possible contribution to the carcinogenesis process in this neoplasia.