The influence of mutational status and biological characteristics of acute myeloid leukemia on xenotransplantation outcomes in NOD SCID gamma mice.

Martin ČulenZdenka KosarovaIvana JeziskovaAdam FoltaJana ChovancovaTomas LojaNikola TomVojtech BystryVeronika JaneckovaDana DvorakovaJiri MayerZdenek Racil

Published in: Journal of cancer research and clinical oncology (2018)

The engraftment of AML was influenced by mutation-interactions and other AML characteristics, rather than by single mutated genes, and engraftment intensity best reflected clinical penetrance of AML.

Keyphrases

acute myeloid leukemia
allogeneic hematopoietic stem cell transplantation
genome wide
hematopoietic stem cell
high intensity
dna methylation
skeletal muscle