The Boring Schwann Cells: Tumor Me-TAST-asis along Nerves.

Published in: Cancer discovery (2022)

Perineural spread is an ominous feature of cancer. Here, Deborde and colleagues describe for the first time the biophysical coupling driving this route of tumor spread and the role of Schwann cell activation in the mobilization of cancer cells within and along the tumor-associated nerves. See related article by Deborde et al., p. 2454 (8).

Keyphrases

induced apoptosis
peripheral nerve
papillary thyroid
single cell
machine learning
cell cycle arrest
deep learning
cell therapy
squamous cell
room temperature
endoplasmic reticulum stress
cell proliferation
signaling pathway
oxidative stress
lymph node metastasis
neural network