Anti-Interleukin-22-Neutralizing Antibody Attenuates Angiotensin II-Induced Cardiac Hypertrophy in Mice.
Jing YeLing LiuQingwei JiYing HuangYing ShiLei ShiJianfang LiuMenglong WangYao XuHuimin JiangZhen WangYingzhong LinJun WanPublished in: Mediators of inflammation (2017)
Our data demonstrated that neutralization of IL-22 alleviated angiotensin II-induced cardiac hypertrophy. The downregulation of IL-22 may be a novel therapeutic strategy to prevent cardiac hypertrophy.