Comparison of Th1 and Th17 Inflammatory Cytokine Profiles Between Chronic Plaque and Acute Guttate Psoriasis.

Hyun Jeong Ju Hyo Jin Park In Hye Choi Kyung Ho Lee Mi Yeon Kwon Chul Jong Park

Published in: Annals of dermatology (2022)

We confirmed that the tissue levels of Th1 and Th17 cytokines were increased in psoriasis patients compared with healthy controls. The increased IFN-γ mRNA level in acute guttate psoriasis and increased IL-12 and IL-17A protein levels in chronic plaque psoriasis suggest that an imbalance between Th1 and Th17 cytokines may play a role in the phenotypic transition of psoriasis.

Keyphrases

liver failure
atopic dermatitis
drug induced
coronary artery disease
respiratory failure
ejection fraction
newly diagnosed
oxidative stress
dendritic cells
immune response
intensive care unit
binding protein
protein protein
hepatitis b virus
small molecule
acute respiratory distress syndrome
patient reported