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Mitochondrial transplantation ameliorates hippocampal damage following status epilepticus.

Xiaoxia JiaQinghua WangJianlun JiWenchun LuZhidong LiuHao TianLin GuoYun Wang
Published in: Animal models and experimental medicine (2023)
To the best of our knowledge, these findings provide the first direct experimental evidence that artificial mitochondrial transplantation is capable of ameliorating hippocampal damage following SE. These new findings support mitochondrial transplantation as a promising therapeutic strategy for epilepsy-associated psychiatric and cognitive disorders.
Keyphrases
  • oxidative stress
  • cell therapy
  • healthcare
  • temporal lobe epilepsy
  • mental health
  • mouse model
  • stem cells
  • mesenchymal stem cells
  • blood brain barrier