A novel long-acting local anesthetic - HTX-011 (ZYNRELEF ™ ) for postoperative pain control.
Ramanjot S KangZhaosheng JinTong J GanPublished in: Expert review of clinical pharmacology (2022)
HTX-011 represents a new tool to help modulate postoperative pain. Although multimodal analgesia has been effective in managing postoperative pain, direct surgical infiltration with local anesthetics has had limited efficacy due to their short duration of action. The HTX-011 formulation provides a long-acting local anesthetic at the surgical site, which provides a longer period of analgesia while maintaining a favorable safety profile.