Treatment of periodontitis and C-reactive protein: A systematic review and meta-analysis of randomized clinical trials.
Shailly LuthraMarco OrlandiSyed Basit HussainHana ChoJoão BotelhoVanessa MachadoJosé João MendesDebora MarlettaSimon HardenFrancesco D'AiutoPublished in: Journal of clinical periodontology (2022)
Treatment of periodontitis reduces serum CRP levels (up to 6 months follow-up) to a degree equivalent to that observed after traditional lifestyle or drug interventions. This evidence supports a causal association between periodontitis and systemic inflammation.