Autotaxin levels in serum and bronchoalveolar lavage fluid are associated with inflammatory and fibrotic biomarkers and the clinical outcome in patients with acute respiratory distress syndrome.

Lijuan GaoXiaoou LiHao WangYue LiaoYongfang ZhouKe WangJun HuMengxin ChengZijian ZengTao WangFu-Qiang Wen

Published in: Journal of intensive care (2021)

The serum ATX level is a potential prognostic biomarker in patients with ARDS. BALF ATX is associated with pulmonary biomarkers of inflammation and fibrosis, suggesting a role of ATX in the pathogenesis of ARDS.

Keyphrases

acute respiratory distress syndrome
extracorporeal membrane oxygenation
mechanical ventilation
oxidative stress
pulmonary hypertension
idiopathic pulmonary fibrosis
intensive care unit
human health