Efficacy of perioperative systemic tranexamic acid along with topical hemocoagulase in decreasing axillary drain output in breast cancer patients undergoing axillary lymph node dissection: A randomized, double-blind, placebo-controlled, superiority trial.
Harshit VermaChandan Kumar JhaPrashant Kumar SinghUpasna SinhaShamshad AhmadJagjit Kumar PandeyManoj KumarPublished in: World journal of surgery (2024)
Perioperative systemic administration of tranexamic acid along with topical application of H to the axillary dissection bed is effective in reducing cumulative axillary drain output after ALND. This strategy may also facilitate earlier removal of suction drains.
Keyphrases
- lymph node
- sentinel lymph node
- patients undergoing
- placebo controlled
- neoadjuvant chemotherapy
- double blind
- phase iii
- ultrasound guided
- study protocol
- phase ii
- early stage
- clinical trial
- cardiac surgery
- wound healing
- acute kidney injury
- locally advanced
- rectal cancer
- radical prostatectomy
- radiation therapy
- phase ii study
- drug induced
- minimally invasive
- young adults