SMR transporters meet the challenge of metformin metabolites.

Published in: The Journal of general physiology (2024)

JGP study (Lucero et al. http://www.doi.org/10.1085/jgp.202313464) shows that members of the SMRGdx subtype can export the degradation products of metformin, helping bacteria adapt to high environmental levels of the commonly prescribed diabetes medication.

Keyphrases

type diabetes
cardiovascular disease
healthcare
ms ms
glycemic control
adipose tissue
human health
skeletal muscle
adverse drug
insulin resistance