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Influence of genetic polymorphisms in vascular endothelial-related genes on the clinical outcome of axitinib in patients with metastatic renal cell carcinoma.

Kazuyuki NumakuraRyoma IgarashiMakoto TakahashiTaketoshi NaraSohei KandaMitsuru SaitoShintaro NaritaTakamitsu InoueTakenori NiiokaMasatomo MiuraTomonori Habuchi
Published in: Cancer biology & therapy (2024)
Our study found that the ACE deletion allele and the NOS3 G allele are associated with increased AEs.
Keyphrases
  • metastatic renal cell carcinoma
  • endothelial cells
  • angiotensin ii
  • angiotensin converting enzyme
  • nitric oxide