Systematic review and Meta-analysis of the Role of total Pancreatectomy as an Alternative to Pancreatoduodenectomy in Patients at High Risk for Postoperative Pancreatic Fistula: is it a Justifiable Indication?

This systematic review and meta-analysis found no reduction in short-term mortality and major morbidity after TP as compared to PD in patients at high-risk for POPF. However, if TP is used as a bail-out procedure, the comparable long-term quality of life is reassuring.