Fast-acting antidepressant-like effects of ketamine in aged male rats.
Elena Hernández-HernándezSandra Ledesma-CorviJordi Jornet-PlazaM Julia García-FusterPublished in: Pharmacological reports : PR (2024)
These results complement prior data supporting a fast-acting antidepressant-like effect of ketamine in rats, to further extend its efficacy to older ages. Future studies are needed to further clarify the lack of response after the repeated treatment as well as its potential adverse effects in aging.