Revamping hemothorax management: The promise of low-dose intrapleural fibrinolytic therapy as an alternative.
Mas Fazlin Mohamad JailainiYusra HashimMohamed Faisal Abdul HamidPublished in: Respirology case reports (2024)
Surgical evacuation has long been the standard treatment for hemothorax. However, some patients are not suitable candidates for surgery. Intrapleural fibrinolytic therapy (IPFT) has recently emerged as an effective alternative for managing retained hemothorax. This case report describes two patients with retained hemothorax who were unfit for surgery and were successfully treated with IPFT at our centre. Both patients were deemed unsuitable for surgery due to comorbidities and their overall functional status. They received three cycles of IPFT, each consisting of 2.5 mg of alteplase. This treatment effectively evacuated the retained hemothorax, achieving complete radiological resolution without immediate or delayed complications up to 3 months post-discharge.
Keyphrases
- end stage renal disease
- minimally invasive
- low dose
- ejection fraction
- newly diagnosed
- chronic kidney disease
- coronary artery bypass
- case report
- prognostic factors
- peritoneal dialysis
- stem cells
- coronary artery disease
- machine learning
- acute coronary syndrome
- patient reported outcomes
- high dose
- big data
- bone marrow
- smoking cessation