Circumventing the packaging limit of AAV-mediated gene replacement therapy for neurological disorders.
Lara MarronePaolo M MarchiMimoun AzzouzPublished in: Expert opinion on biological therapy (2022)
The field of AAV-gene therapy has experienced enormous advancements in the last decade. However, there is still ample space for improvement aimed at overcoming existing challenges that are slowing down the progressive trajectory of this field.