Login / Signup

Loss of retinal tension and permanent decrease in retinal function: a new porcine model of rhegmatogenous retinal detachment.

Nina Buus SørensenAnders Tolstrup ChristiansenTroels Wesenberg KjaerKristian KlempMorten la CourSteffen HeegaardKarin WarfvingeJens Folke Kiilgaard
Published in: Acta ophthalmologica (2019)
Loss of retinal tension in the detached retina seems to induce permanent damage with loss of retinal function. Death of ganglion cells, observed as soon as 2 weeks after detachment, explains the permanent loss of retinal function. The new model enables investigations of time-relationship between retinal detachment and lasting damage in addition to exploration of novel treatment modalities.
Keyphrases
  • diabetic retinopathy
  • optical coherence tomography
  • optic nerve
  • oxidative stress
  • induced apoptosis
  • cell proliferation
  • spinal cord injury
  • signaling pathway
  • spinal cord